Journal of Liver Cancer

Chae Yoon Chon

1 Article

Two Cases of Acute Hepatic Decompensation after Concurrent Chemoradiotherapy in Patients with Advanced Hepatocellular Carcinoma: Myoung Hwan Kim, Sang Hoon Ahn, Yong Han Paik, Kwan Sik Lee, Chae Yoon Chon, Young Myoung Moon, Jinsil Seong, Kwang Hyub Han; Journal of the Korean Liver Cancer Study Group. 2005;5(1):52-56. Published online June 30, 2005

Abstract PDF: Advanced hepatocellular carcinoma with portal vein thrombosis has a poor prognosis. Concurrent chemoradiation (CCRT) therapy achieved favorable results in advanced hepatocellular carcinoma with portal vein thrombosis and can be considered as a treatment option for the management of advanced hepatocellular carcinoma.2 But, exacerbation of liver function during concurrent chemoradiotherapy is a critical complication in patients with hepatitis B virus (HBV) related HCC. Reactivation of HBV replication is a well-known complication in cancer patients receiving chemotherapy. We report two cases with acute exacerbation of liver function. The one
result
ed in hepatic decompensation after CCRT probably due to HCC progression and/or chemoradiotherapy and the other is due to reactivation of HBV replication after CCRT, who recovered after lamivudine and corticosteroid therapy.

Chae Yoon Chon

1 Article

A Case of Successful Treatment for Recurrent Hepatocellular Carcinoma with Long term Survival: Jin Hyoung Lee, Ja Kyung Kim, Hwa Sook Kim, Sang Hoon Ahn, Chae Yoon Chon, Young Myoung Moon, Kwang-Hyub Han, Woo Jung Lee, Young Nyun Park, Seung Hyoung Kim, Kwang Hoon Lee, Do Yun Lee, Jong Tae Lee; Journal of the Korean Liver Cancer Study Group. 2006;6(1):20-24. Published online June 30, 2006

Abstract PDF: The long term results of surgery for hepatocelluar carcinoma are not satisfactory, because the high incidence of intrahepatic tumor recurrence, with a 5-year acturial recurrence rate of 75% to 100%. The risk factors for postoperative recurrence such as venous invasion, presence of satellite nodules, large tumor size, advanced TNM stages are the best-established. For the management of postoperative recurrence, studies largely focused on the recurrence in the remnant liver. The therapeutic modalities commonly used for surgical resection, TACE, percutaneous ethanol injection (PEIT), and systemic chemotherapy. We report a case of recurrent hepatocellular carcinoma after curative resection, successfully treated by TACE, TACI, and systemic chemotherapy with long term survival.